The nRF52820 is a System-on-Chip (SoC) offering USB and advanced wireless connectivity in a small package, for HID, smart home, commercial, and industrial applications.

The nRF52820 features an Arm Cortex-M4 processor, clocked at 64 MHz. It has 256 KB Flash and 32 KB RAM, and a range of analog and digital interfaces such as an analog comparator, UART, SPI, TWI, QDEC, and last but not least, USB. It can be supplied with a voltage from 1.7 to 5.5 V which enables powering the device from sources such as rechargeable batteries or via USB. The 2.4 GHz multiprotocol radio is fully featured and provides up to +8 dBm output power.

nRF52820 supports all Bluetooth Low Energy features, including Direction Finding, high-throughput 2 Mbps, Long Range more Bluetooth LE features. It also supports Bluetooth mesh, Thread and Zigbee mesh protocols. 

The nRF52820's USB peripheral implements a Full Speed USB 2.0 device that offers a widely-used interface that enables low-latency and high-bandwidth communication with a range of hosts, such as PCs, tablets, smartphones, and gateways. It also adds the option of performing device firmware updates (DFU) over USB. When connected to a USB host, the nRF52820 can be directly powered by the always-present 5 V VBUS signal.